Stella Bella Pure Active Serum

Active Ingredient: Syn-Coll

Attributes:  Mimics the human body’s own mechanism to produce Collagen.

Effect: The clinical effect on wrinkles is a 350% improvement compared to placebo

Ingredients: Deionized water, Glycerin, Palmitoyl Tripeptide 3, Hibiscus flower extract(cert. Organic)Gluconolactone and Sodium Benzoate.

Spec Sheet:

What is it?

Stella Bella Active Serum is a new cosmeceutical serum using the patented technology based on Pentapharm’s many years of experience in synthesizing peptides for the pharmaceutical industry.  Our Actives serum contains only the active ingredient in a carrier solution. No fragrance or fillers are used so penetration is not interrupted and results exceed those of crèmes containing the active ingredient. Syn-Coll is a small peptide with the unique sequence to mimic the human body’s own mechanism to produce collagen via TGF-B(tissue growth factor).  Syn-Coll is offered unpreserved and is prepared as a ready to use water soluble solution that can be used directly or mixed with any other leave on skin care product.

Properties:  Collagen represents the main component of the ECM(Extra Cellular Matrix) of the dermal connective tissue.  Thrombospondin1(TSP) is a multifunctional protein that activates the latent but biologically inactive form of TGF-B. TGF-B is known as the key element in the synthesis of collagen and binds to a particular sequence in the TSP molecule. This sequence is known as ARG-PHE-LYS, being similar to this, SYN-COLL also has the capacity to bind and therefore activate TGF-B.

Function:  Syn-Coll stimulates Collagen synthesis-excellent healing capabilities for use during radiation or after chemical peeling, laser resurfacing or other invasive procedures.

                    Syn-Coll actively removes ANY type of wrinkle

                   Syn-Coll also has firming and moisturizing qualities

Properties:  Syn-Coll has been clinically proven to be safe AND EFFECTIVE

Cosmetic Application:  Syn-Coll is a deep penetrating, bio-active ingredient developed to remove any type of wrinkle and to repair existing stretch marks. Note: Syn-Coll has not been clinically proven to remove  hypertrophic or keloid scars.

As a breakthrough in wrinkle treatment Syn-Coll can be used in any type of anti-aging product for the aspect of wrinkle reduction.

Suggested Concentration:  1-3% Syn-Coll. Most cosmetic preparations contain 1% *Our serum is a 5% solution (at 3 drops per application:

Cost:  79.50 for 1/2 oz. 1/2 oz = approximately 500 drops. (Doctors and Medical Facilities please call for wholesale pricing.) At double the recommended dosage, this bottle will last  180 days using the serum 2x a day at 6 drops per application. Stability for at least one year.

Efficacy  tests:  In vitro testing in human fibroblasts, Syn-Coll has shown excellent collagen building capacity compared to the positive standard TGF-B(0.4nM) There is an increase of collagen synthesis by 119% compared to the positive standard.

Efficacy tests:
In vitro testing in human fibroblasts, SYN®-COLL has shown excellent collagen building capacity compared to the positive standard TGF-β (0.4 nM).

In vitro test:

To prove the wrinkle repairing effect of Syn-Coll, a study on 60 healthy volunteers has been performed. Various concentrations of Syn-Coll (1% and 2.5% respectively) have been applied twice daily for 84 days.